Effect of diet and exercise on blood glucose levels

 
Diet and exercise alone are often insufficient to achieve optimal glycemic control. Hypoglycemic medicines taken by mouth - mainly sulfonylureas - are widely used in the treatment of type II diabetes. The main mechanism of action is to increase the sensitivity (the beta cells to glucose, so that beta-cell releases more insulin at each level of glucose in the blood. The best candidates for the application of sulfonylureas are patients with levels of fasting blood glucose less than 250 mg / dL .

 
Treatment strategy for patients with failure of oral hypoglycemic agents.

• "Short Course" insulin;
• Weight loss in the hospital and change eating behavior;
• Intensive outpatient program (weekly visits to the doctor);
• Acceptance of insulin at night, and sulfonylurea in the daytime.   

A patient with type II diabetes can join a group or insulin-resistant patients with insuligyuvoy failure. For example, a patient has only recently fallen ill with diabetes nearly "ideal" body weight (not obese) may actually be latently flowing type I diabetes, even without ketosis. In these patients, despite the absence of antibodies against pancreatic islet cells in serum, it is advisable to start insulin therapy in the period of diagnosis. 

This can save the residual function (beta cells and strengthen control over the course of the disease in the future. And, finally, an extensive list of used drugs can disrupt glucose tolerance, and many of the drugs used in diabetes patients for the treatment of opportunistic diseases.

Caution should be exercised in the preparation of schemes treatment to using these drugs to achieve the best therapeutic results with the least negative effect. As a result, drug therapy type II diabetes is a balancing optimization of control over the content of blood sugar while simultaneously trying to improve insulin sensitivity by changing lifestyles.
 

The order of treatment insulinneeavisimogo diabetes. 

• Control of blood glucose (fasting <120 after meals <200 mg / dL);
• To minimize the dose of drugs;
• nausea and hypertension the concentration of lipids by means that do not break tolerance to glucose.